Systematic Review & Meta-Analysis Service

PRISMA 2020 meta-analysis service: search strategy, dual screening, effect-size pooling, I² and publication-bias diagnostics. Reproducible R or RevMan output.

The Celsus meta-analysis service is built for theses, journal articles and projects that need a systematic review protocol. We turn the scattered findings of individual studies into a transparent, reproducible evidence synthesis that meets the PRISMA 2020 standard. For researchers in the health sciences, education, psychology and the social sciences, we deliver a quantitative synthesis that is defensible under peer review and ready for journal submission.

What's included

  • Framing the research question with PICO/PECO and drafting the protocol (including a PROSPERO registration draft where appropriate).
  • Building the database search strategy (PubMed, Scopus, Web of Science, PsycINFO) with fully documented, reproducible search strings.
  • Dual screening by two independent reviewers, conflict resolution and a Cohen's kappa agreement report.
  • Data extraction from included studies and risk-of-bias assessment (RoB 2 / ROBINS-I).
  • Computing and pooling effect sizes under both fixed- and random-effects models.
  • Heterogeneity (I², τ², Q), publication-bias diagnostics (funnel plot, Egger's test, trim-and-fill) and sensitivity analyses.
  • PRISMA flow diagram, forest plot, funnel plot and a submission-ready methods write-up, with all R/RevMan code and data.

How we work

  1. Scope: We discuss your research question, eligibility criteria and target journal, draft the protocol and send a scoped fixed quote within one working day.
  2. Preparation: We build the search strategy, run the dual screening and standardise the extraction sheet, documenting every step so it can be audited.
  3. Analysis: We pool effect sizes, test heterogeneity and publication bias, and run subgroup and sensitivity analyses.
  4. Reporting and aftercare: We deliver the PRISMA-compliant results section, the figures and the reproducible code, and support any extra analyses requested during peer review.

Meta-analysis steps and deliverables

Each step of the systematic review and meta-analysis workflow, its deliverable and the tool used.
StepDeliverableTool
Protocol and search strategyPICO framework, search strings, PROSPERO draftRayyan, reference manager
Study selectionDual-screening records, kappa agreement, PRISMA flow diagramRayyan
Data extraction and biasExtraction sheet, RoB 2 / ROBINS-I appraisalExcel, robvis
Effect-size poolingForest plot, pooled estimate and confidence intervalR (metafor), RevMan
Heterogeneity diagnosticsI², τ², Q statistic; subgroup analysisR (metafor)
Publication biasFunnel plot, Egger's test, trim-and-fillR (metafor)
ReportingPRISMA-compliant text, figures, reproducible codeR Markdown / RevMan

The growth of meta-analysis publishing

148.0115.583.050.518.0201020132016201920222025
An illustrative trend showing growing interest in the meta-analysis method over time; not actual indexing data.

If you would like to understand the method in more depth, our meta-analysis and PRISMA guide is a good starting point. To decide which effect size suits your data, see our guide to effect sizes, and for how to report the results consult our APA 7 statistics reporting checklist.

Frequently Asked Questions

How long does a meta-analysis take?

It depends on the number of included studies and the breadth of the search. A narrowly scoped review can take a few weeks, while a large literature takes longer. Once the scope is clear we share a realistic timeline.

How is the price determined?

We base the price on scope factors such as eligibility criteria and analytical depth. You receive a scoped fixed quote within one working day, with no surprise charges along the way.

Is my data and draft kept safe?

All materials are kept confidential. We sign a non-disclosure agreement on request and our work is aligned with UK GDPR and KVKK. Your data is deleted on completion if you ask us to.

How do I get started?

Send your research question and eligibility criteria through the contact form or via WhatsApp. We draft the protocol and reply with a scoped fixed quote within one working day.

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